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KMID : 0379119860140030195
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Korean Journal of Mycology
1986 Volume.14 No. 3 p.195 ~ p.200
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Specific Conversion of Ginseng Saponin by the Enzyme of Phizopus japonicus
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Abstract
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The enzyme produced by a strain of Rhizopus japonicus was able to covert selectively ginsenoside Rb₁ which was the most abundant ginseng saponin, into ginsenoside Rd which was known to be superior to ginsenoside Rb₁ pharmaceutically. This specific conversion of ginsenoside Rb₁ without any change of other ginsenoside patterns was confirmed by thin layer chromatography and high performance liquid chromatograpy quantitatively. The amount of ginsenoside Rd was increased to 4.8 and 34.7 folds by enzymatic conversion of ginsenoside Rb₁ in total saponin and ginsenoside Rb group saponin, respectively. The increased amount of ginsenoside Rd corresponded to total amount of released glucose and decreased amount of ginsenoside Rb₁ accurately.
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